2960 Chartres St. | LaSalle, IL 61301
info@ncbhs.org

Depression: Depression & Related Conditions
Resources
Basic Information
Introduction and Types of Depressive DisordersRelated Disorders / ConditionsHistorical and Current UnderstandingsBiology, Psychology and SociologyTreatment - Medication and PsychotherapyAlternative Medicine and Self-Help ResourcesSpecial IssuesReferences
More InformationTestsLatest News
Hey Fellas, Depression Can Strike New Dads, TooDepression Often Untreated in Dialysis PatientsGDM Found to Increase Risk for Postpartum DepressionPostpartum Depression Affects New Dads, TooPanic Disorder May Up Odds of Depression Rx Side EffectsSometimes the Holidays Aren't Always JollyPilots Suffer Depression, Suicidal Thoughts at Fairly High RatesMore Than 1 in 10 Pilots Suffer From Depression, Survey FindsSelf-Care Tools Cut Depression in AMD, Diabetic RetinopathyClinical Antecedents of Adolescent-Onset MDD IdentifiedAge-Related Cataract Linked to Depressive SymptomsDepression, Suicide Ideation Prevalent in Medical Students2 Out of 3 Depressed Teens Gain Lasting Benefits From TherapyAntidepressants + Exercise Beneficial in Late-Life DepressionDepressed Women Less Likely to Get Best Breast Cancer Care: StudyDepression on the Rise Among U.S. Teens, Especially GirlsMemantine + Sertraline Effective for Major Depressive DisorderDepressive Symptoms Linked to Functional Status in CADHigh Rate of Antidepressant Use After CancerResearchers Find Antidepressant Bupropion Crosses PlacentaSome Antihypertensives Linked to Depression, Bipolar RiskMom-to-Be's Antidepressant Use May Be Tied to Speech Issues in ChildDepression Can Fuel Heart Disease in Midlife Women: StudyDepression Common in Patients With Chronic Angina'The Pill' May Raise Depression RiskFacebook Bullying Can Cause DepressionStroke Survivors Often Struggle With DepressionMany Cases of Depression in Adults Not Being TreatedMany Depressed Adults Not Getting Treatment: StudyMajor Depressive Disorder Ups Acute MI Risk in HIV-InfectedPostpartum Depression Can Be ID'd During Infant HospitalizationDepression Common After Time Spent in ICUStudy Finds Links Between Chronic Pain, Depression in CouplesDepression Can Stalk Families Through GenerationsScientists Spot 15 Regions of Human DNA Linked to DepressionBehavioral Activation Therapy Viable Option in DepressionCould New 'Talk Therapy' Cut Cost of Treating Depression?Baseline Depression Symptoms Tied to Low Med AdherenceDepression Linked to CKD in Patients With DiabetesDiabetic Retinopathy Independently Tied to DepressionDepression Strikes Nearly 3 Million U.S. Teens a YearDepression Plagues Many With COPDPersistent Depression Linked to Increased CAC Scores in WomenReview Finds Antidepressants Ineffective in Children, TeensStudy Questions Use of Antidepressants for Children, TeensDepressive Symptoms Linked to Reduced FecundabilityScans Spot Brain Region That Misfires in Depressed PeopleScientists Test 'Magic Mushroom' Chemical for Tough-to-Treat DepressionWhole-Body Hyperthermia May Help Ease Depression SymptomsCould Inducing Brief, Mild 'Fever' Help Ease Depression?
Questions and AnswersVideosLinksBook Reviews
Related Topics

Anxiety Disorders
Bipolar Disorder
Suicide
Addictions: Alcohol and Substance Abuse
Pain Management

Clinical Antecedents of Adolescent-Onset MDD Identified


HealthDay News
Updated: Dec 12th 2016

new article illustration

MONDAY, Dec. 12, 2016 (HealthDay News) -- Irritability and fear and/or anxiety are significant clinical antecedents of new adolescent-onset major depressive disorder (MDD) in individuals at familial risk, according to a study published online Dec. 7 in JAMA Psychiatry.

Frances Rice, Ph.D., from Cardiff University in the United Kingdom, and colleagues conducted a four-year longitudinal study to examine the developmental pathways that lead to first-episode adolescent-onset MDD among offspring of depressed parents. Participants included 337 families with an index parent who had experienced at least two episodes of MDD and who had a biologically-related child aged 9 to 17 years living with the index parent.

The researchers found that at follow-up, the offspring had a mean of 1.85 Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV) symptoms of MDD. Twenty adolescents had new-onset MDD (mean age at onset, 14.4 years). Significant independent clinical antecedents of new adolescent-onset MDD included irritability and fear and/or anxiety, but not disruptive behavior and low mood. Similar results were seen for the DSM-IV symptom count at follow-up. All measured familial/genetic and social risk indicators influenced the risk of new-onset MDD directly, rather than through dimensional clinical antecedents.

"There are multiple pathways to first-onset adolescent depression in individuals at familial risk," the authors write. "Irritability and fear/anxiety may be additional clinical phenomena to be included as targets in primary preventive interventions focusing on the child."

Full Text
Editorial (subscription or payment may be required)