2960 Chartres St. | LaSalle, IL 61301
info@ncbhs.org

Depression: Depression & Related Conditions
Resources
Basic Information
Introduction and Types of Depressive DisordersRelated Disorders / ConditionsHistorical and Current UnderstandingsBiology, Psychology and SociologyTreatment - Medication and PsychotherapyAlternative Medicine and Self-Help ResourcesSpecial IssuesReferences
More InformationTestsLatest News
Depression Inversely Linked to Body Composition in TeensReview: Depression Screening As Inpatient Important, FeasibleDepression Can Slow Hospital Patients' Recovery: StudyAntidepressants During Pregnancy Safe for Baby: StudyChronic Pain Common in Adults With Depression, AnxietyWhat You Need to Know About AntidepressantsAPA: Internet-Based CBT Can Be Helpful in DepressionCan Online Treatment Replace Your Therapist?Depression Often a Precursor to Falls in Elderly PeopleOverweight in Childhood May Up Lifetime Risk of DepressionHeavy Kids Face Triple the Odds for Depression in AdulthoodObesity, Sex Predict Remission for Antidepressant MedicationsGender Differences in Depression Tend to Appear About Age 12Depression's Gender Gap Shows Up in Pre-Teen YearsStudies Question Link Between Mom's Antidepressant Use, Autism in KidsMortality Up With Depression Just Before Breast Cancer DiagnosisDepressive Disorders Up With Antimuscarinics for OABTrauma as a Teen May Boost Depression Risk Around MenopauseBlood Test Promising for ID of Early Depression, SchizophreniaBlood Test Might Someday Distinguish Early Depression, SchizophreniaHold That Pose: Yoga May Ease Tough DepressionDepression May Hasten Death in Years After Heart DiagnosisAntidepressant Efficacy Varies for Depressive Symptom ClustersDepressed Psoriasis Patients at Higher Risk of Psoriatic ArthritisInternet-Based CBT Effective for Depressive SymptomsCan Depression Up Odds for Arthritis Linked to Psoriasis?Postpartum Depressive Symptoms Fell in 2004 to 2012Hey Fellas, Depression Can Strike New Dads, TooDepression Often Untreated in Dialysis PatientsGDM Found to Increase Risk for Postpartum DepressionPostpartum Depression Affects New Dads, TooPanic Disorder May Up Odds of Depression Rx Side EffectsSometimes the Holidays Aren't Always JollyPilots Suffer Depression, Suicidal Thoughts at Fairly High RatesMore Than 1 in 10 Pilots Suffer From Depression, Survey FindsSelf-Care Tools Cut Depression in AMD, Diabetic RetinopathyClinical Antecedents of Adolescent-Onset MDD IdentifiedAge-Related Cataract Linked to Depressive SymptomsDepression, Suicide Ideation Prevalent in Medical Students2 Out of 3 Depressed Teens Gain Lasting Benefits From TherapyAntidepressants + Exercise Beneficial in Late-Life DepressionDepressed Women Less Likely to Get Best Breast Cancer Care: StudyDepression on the Rise Among U.S. Teens, Especially GirlsMemantine + Sertraline Effective for Major Depressive DisorderDepressive Symptoms Linked to Functional Status in CADHigh Rate of Antidepressant Use After CancerResearchers Find Antidepressant Bupropion Crosses PlacentaSome Antihypertensives Linked to Depression, Bipolar RiskMom-to-Be's Antidepressant Use May Be Tied to Speech Issues in ChildDepression Can Fuel Heart Disease in Midlife Women: Study
Questions and AnswersVideosLinksBook Reviews
Related Topics

Anxiety Disorders
Bipolar Disorder
Suicide
Addictions: Alcohol and Substance Abuse
Pain Management

Baseline Depression Symptoms Tied to Low Med Adherence


HealthDay News
Updated: Jul 18th 2016

new article illustration

MONDAY, July 18, 2016 (HealthDay News) -- Among clinical and sociodemographic characteristics, only baseline depressive symptoms are tied to low medication adherence in teen patients with type 2 diabetes, according to a study published online June 28 in Diabetes Care.

Lorraine Levitt Katz, M.D., from the Children's Hospital of Philadelphia, and colleagues randomized 699 low-socioeconomic status patients (aged 10 to 17 years old) with recent-onset type 2 diabetes and ≥80 percent adherence to metformin therapy for at least eight weeks during a run-in period to either metformin alone, metformin plus rosiglitazone, or metformin plus an intensive lifestyle program.

The researchers found that sex, age, family income, parental education, or treatment group did not differentiate high and low adherence. Adherence declined over time (72 percent high adherence at two months and 56 percent adherence at 48 months; P < 0.0001). More participants with low adherence had clinically significant depressive symptoms at baseline (18 versus 12 percent; P = 0.0415). Loss of glycemic control was not predicted by any adherence threshold.

"Medication adherence was positively associated with insulin sensitivity and oral disposition index, but, because of disease progression, adherence did not predict long-term treatment success," the authors write.

One author disclosed financial ties to the pharmaceutical industry, which supported the TODAY study.

Full Text (subscription or payment may be required)